Publications

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Selected Research Papers

Issler O, van der Zee YY, Ramakrishnan A, Xia S, Zinsmaier AK, Tan C, Li W, Browne CJ, Walker DM, Salery M, Torres-Berrío A, Futamura R, Duffy JE, Labonte B, Girgenti MJ, Tamminga CA, Dupree JL, Dong Y, Murrough JW, Shen L, Nestler EJ. (2022) The Long Noncoding RNA FEDORA is a Cell-Type- and Sex-Specific Regulator of Depression. Science Advances, 8(48):eabn9494

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Van der Zee YY, Lardner CK, Walker DM, Torres-Berrío A, Ramakrishnan A, Parise EM, Alvarez K, Cunningham AM, Rutten B, Shen L, Murrough JW, E. J. Nestler† and Issler O†. (2022) Blood miR-144-3p: A novel diagnostic and therapeutic tool for depression. Molecular Psychiatry, 27(11): 4536–4549.

†Co-corresponding authors

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Issler O, van der Zee YY, Ramakrishnan A, Wang J, Tan C, Loh YHE, Purushothaman I, Walker DM, Lorsch ZS, Hamilton PJ, Peña CJ, Flaherty E, Hartley BJ, Torres-Berrío A, Parise EM, Kronman H, Duffy JE, Estill MS, Calipari ES, Labonté B, Neve RL, Tamminga CA, Brennand KJ, Dong Y, Shen L, and Nestler EJ. (2020) Sex-specific role for the long non-coding RNA LINC00473 in depression. Neuron, 106(6):912-926.

International Society of Psychiatric Genetics (ISPG) Gershon Paper of the Year

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Issler O, Haramati, S, Paul E, Maeno H, Navon I, Zwang R, Gil S, Mayberg HS, Dunlop BW, Menke A, Awatramani R, Binder EB, Deneris ES, Lowry CA and Chen A. (2014) MicroRNA 135 is essential for chronic stress resiliency, antidepressant efficacy and intact serotonergic activity. Neuron, 83(2):344-60.

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Selected Reviews and Book Chapters

Issler O, Lorsch ZS and Nestler EJ. Molecular characterization of the resilient brain: transcriptional and epigenetic mechanisms. Stress Resilience, Chapter 15. Editor Chen A, Elsevier, 2019.

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Issler O and Chen A. (2015) Determining the role of microRNAs in psychiatric disorders. Nature Reviews Neuroscience, 16(4):201-12.

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Popular Writings

Issler O (2024) From DNA’s dark corners: fresh clues about depression. The Biochemist

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